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G1/S arrest inhibits Bim upregulation and maintains Erk phosphorylation following growth factor withdrawal. MCF-10A cells transduced with control vector (BABE) or BABE encoding p21Cip1 were cultured with (++) or without (−−) EGF for 24 h and analyzed for Bim expression and Erk phosphorylation (p-Erk1/2) as described for Fig. 6.
