Table 2.
Laboratory and Imaging Results
| Laboratory Data | ||
|---|---|---|
| Laboratory Test | Normal Results | Results |
| Hematology | ||
| Absolute CD4+ lymphocytes, mm3 | 458-1,344 | 26 |
| CD8+ lymphocytes, % | 10-36 | 22.4 |
| CD19+ lymphocytes, % | 6-19 | 2.3 |
| Serology | ||
| IgG, mg/dL | 610-1,616 | 529 |
| IgA, mg/dL | 61-348 | 99 |
| IgM, mg/dL | 35-242 | 41 |
| Free kappa light chains, mg/L | 7.0-27.0 | 65.4 |
| Free lambda light chains, mg/L | 5.6-26.3 | 55 |
| Kappa/lambda ratio | 0.26-1.65 | 1.19 |
| Influenza type A and B titers | 1:16, 1:8 | |
| Measles, rubeola, IgG, AU/mL | 288 | |
| Varicella IgG, CU | >4,000 | |
| Antinuclear antibody titer | 1/160 | |
| Microbiology | ||
| HIV-1/2 antigen/antibody screen | Nonreactive | |
| Hepatitis C antibody screen | Nonreactive | |
| Hepatitis B Core antibody, IgG + IgM | Nonreactive | |
| CMV viral load | Not detected | |
| EBV viral load | Not detected | |
| HHV-6 viral load | Not detected | |
| HTLV-I/II antibody screen | Nonreactive | |
| Alpha-1-antitrypsin, stool, mg/dL | <55 | 1,320 |
| Protein, urine, 24-h, mg/24 h | 0-100 | 384 |
| Imaging and Other Findings | |
|---|---|
| Imaging Test | Findings |
| Computed tomography scan of the chest | Pericardial effusion, moderate to large right pleural effusion. |
| Positron emission tomography scan | FDG uptake in pericardial space consistent with known infectious pericarditis, bilateral pleural effusions with adjacent atelectasis, and few mediastinal and left supraclavicular lymph nodes. |
| Flow cytometry (blood) | No definitive phenotypically abnormal population identified. Specimen with mixture of cell types. No increased blasts. Most lymphocytes are mature T cells, and the B cells comprise a mixture of kappa- and lambda-positive cells. T cells present comprise CD4+ and CD8+ cells with latter predominating (inverted CD4/CD8 ratio 0.2). |
CMV = cytomegalovirus; EBV = Epstein-Barr virus; FDG = fluorodeoxyglucose; HHV = human herpesvirus; HIV = human immunodeficiency virus; HTLV-I/II = human T-lymphotropic virus 1 and 2; Ig = immunoglobulin.