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. 2024 Sep 3;3:1442006. doi: 10.3389/frtra.2024.1442006

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© 2024 Huelsboemer, Moscarelli, Dony, Boroumand, Kochen, Knoedler, Yu, Hauc, Stögner, Formica, Lian, Murphy, Pomahac and Kauke-Navarro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Acute rejection episodes of hand and face transplants classified by banff 2007 rejection grade with C4d and DSA status. For hand and face transplants combined, mean rejection grade was found to be significantly higher in episodes reported positive for DSA (p = 0.005) but was not found to be different between episodes reported positive or negative for C4d (p = 0.33). Mean rejection grade was also not found to be significantly different based on status of either marker for isolated hand or face transplants (Hand Only: C4d; p = 0.42, DSA; p = 0.15, Face Only: C4d; p = 0.50, DSA; p = 0.61).