TABLE 4.
Genotype |
URA3
|
CAN1
|
||
---|---|---|---|---|
Loss rate at RDN1b | Fold increase | Loss rate at LYS2 | Fold increase | |
wt | 1.3 × 10−7 | 1 | 6.6 × 10−8 | 1 |
sgs1 | 9.6 × 10−7 | 4.8 | 42 × 10−8 | 6.4 |
rmi1 | 36 × 10−7 | 28 | 140 × 10−8 | 21 |
rmi1 sgs1 | 3.2 × 10−7 | 2.5 | 30 × 10−8 | 4.5 |
Strains are K1875, NJY540, JMY1996, and JMY1997.
Marker loss rates (per cell per generation) were calculated by the method of the median as previously described (49).