Table 3.

Analysis of the association between genetic models and sporadic TAAD risk

SNP	Genetic model	GT	OR	95% CI	p
TGF-β1 rs1800469	Dominant	(AA + AG)/GG	0.863	0.461–1.616	0.645
	Recessive	AA/(AG + GG)	1.144	0.598–2.189	0.684
	Additive	AA	1
		AG	0.820	0.415–1.619	0.568
		GG	1.006	0.456–2.223	0.987
TGF-β2 rs900	Dominant	(AA + AT)/TT	0.796	0.465–1.360	0.403
	Recessive	AA/(AT + TT)	1.303	0.412–4.117	0.652
	Additive	AA	1
		AT	0.654	0.198–2.156	0.485
		TT	0.867	0.268–2.812	0.813
TGFBR2 rs764522	Dominant	(CC + CG)/GG	2.559	0.459–14.276	0.284
	Recessive	CC/(CG + GG)	0.757	0.390–1.470	0.411
	Additive	CC	1
		CG	1.578	0.771–3.227	0.212
		GG	0.425	0.076–2.381	0.33
TGFBR2 rs1036095	Dominant	(CC + CG)/GG	2.447	1.324–4.521	0.004*
	Recessive	CC/(CG + GG)	0.147	0.018–1.200	0.073
	Additive	CC	1
		CG	0.257	0.030–2.203	0.215
		GG	0.12	0.015–0.984	0.048*
TGFBR2 rs6785385	Dominant	(AA + AG)/GG	0.65	0.362–1.169	0.15
	Recessive	AA/(AG + GG)	0.383	0.069–2.139	0.274
	Additive	AA	1
		AG	2	0.339–11.785	0.444
		GG	2.889	0.513–16.255	0.229
FBN-1 rs10519177	Dominant	(AA + AG)/GG	1.842	0.886–3.829	0.102
	Recessive	AA/(AG + GG)	1.379	0.795–2.390	0.253
	Additive	AA	1
		AG	0.838	0.464–1.513	0.557
		GG	0.495	0.224–1.096	0.083
FBN-1 rs1036477	Dominant	(AA + AG)/GG	2.067	0.654–6.537	0.216
	Recessive	AA/(AG + GG)	2.105	1.205–3.677	0.009*
	Additive	AA	1
		AG	0.495	0.275–0.892	0.019*
		GG	0.379	0.118–1.223	0.105
FBN-1 rs2118181	Dominant	(CC + CT)/TT	0.475	0.272–0.830	0.009*
	Recessive	CC/(CT + TT)	0.484	0.153–1.529	0.216
	Additive	CC	1
		CT	1.305	0.388–4.394	0.667
		TT	2.635	0.818–8.493	0.105
MYH11 rs117593370	Dominant	(CC + CT)/TT	—
	Recessive	CC/(CT + TT)	1.706	0.373–7.811	0.491
	Additive	CC	1
		CT	0.586	0.128–2.683	0.491
		TT	—
MYH11 rs115364997	Dominant	(AA + AG)/GG	0.652	0.058–7.303	0.729
	Recessive	AA/(AG + GG)	0.654	0.320–1.337	0.245
	Additive	AA	1
		AG	1.519	0.727–3.177	0.267
		GG	1.646	0.147–18.488	0.686

*Significant P-values (a P-value of less than 0.05).