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. 2024 Sep 12;19:9487–9502. doi: 10.2147/IJN.S479123

Figure 7.

Figure 7

HE staining micrograph of organs from sacrificed mice in combination with CTLA-4 checkpoint blockade.

Notes: HE micrograph of tumor slices from four groups that received CTLA-4 antibodies. No signs of cell necrosis or organ damage were indicated in major organs, including the heart, lung, liver, kidney and spleen. Scale bar: 100μm.

Abbreviations: HE, hematoxylin and eosin; QDs-RGD, quantum dots conjugated with arginine-glycine-aspartic acid peptide sequence; YLG-1, (17R,18R)-2-(1-hexyloxyethyl)-2-devinyl chlorine E6 trisodium salt; PBS, phosphate-buffered saline; PDT, photodynamic therapy; CTLA-4, cytotoxic T lymphocyte-associated antigen-4.