Figure 9.

The anticancer effect of cannabinoid-containing products is by telomere lengthening and upregulation of P53: telomeres are repeating nucleotide sequences at the ends of chromosomes that protect the chromosome ends from damage and degradation. Telomeres shorten at each cell division, and cells die when they become too short. Telomere shortening results in aging and the absence of cancer. Overexpression of telomerase, the enzyme responsible for telomere lengthening, leads to genetic instability, tumors, and cancer development. Overexpression of telomerase, telomere lengthening, and upregulation of tumor suppressor P53 leads less aging and absence of cancer. “Created with Biorender.com”