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. 2024 Aug 21;9(9):e00794-24. doi: 10.1128/msystems.00794-24

Fig 7.

Illustration compares control and B-CS groups, depicting colon histology, immunostaining for claudin and ZO-1, and cytokine levels. It highlights inflammation, differences in tight junction proteins, and elevated cytokine levels in the B-CS group.

CS-FMT impaired intestinal barrier and imbalanced cytokines of mice. (A) Histological examination of colon. The sections were stained with H&E. Original magnification, ×200. (B) Immunohistochemistry determination of ZO-1 and Occludin expression in the colon tissue of mice. Original magnification, ×200. (C) Immunofluorescent analysis of ZO-1 and Occludin in the colon tissue of mice. Original magnification, ×200. (D) A total of 7 cytokines (IL-5, IL-6, IL-9, IL-10, IL-17A, IL-17F and IL-13) were found to be significantly altered in the peripheral serum of B-CS-FMT mice. *P < 0.05, **P < 0.01, ***P < 0.001.