Table 1.
Characteristics of sudden cardiac death cases
| Sample ID | Gender | Age | Event at death | Symptoms at death | Weight (kg) × height (cm) | Heart weight (g) | Autoptic diagnosis | Sample type |
|---|---|---|---|---|---|---|---|---|
| SCD01 | M | 26 | Sport | Syncope | 85 × 175 | 700 | HCM | FFPET |
| SCD02 | M | 29 | Sleep | Dyspnoea | 71 × 174 | n/a | SAD | n/a |
| SCD03 | M | 22 | Sport | Syncope | 87 × 171 | 365 | HCM | FFPET |
| SCD04 | M | 36 | Light activity | n/a | n/a | n/a | SAD | n/a |
| SCD05 | M | 29 | Sleep | None | 70 × 177 | 340 | SAD | FFPET |
| SCD06 | M | 37 | Rest | None | 63 × 172 | 350 | SAD | FFPET |
| SCD07 | M | 20 | Sport | Syncope | n/a × 175 | 500 | AC (RV, LV) | FFPET |
| SCD08 | M | 25 | Sleep | None | 77 × n/a | 370 | SAD | FFPET |
| SCD09 | F | 25 | n/a | n/a | n/a | n/a |
Non-diagnostic autopsy findings (MVP) |
n/a |
| SCD10 | M | 21 | Sport | Syncope | 90 × 187 | 520 | DCM | FFPET |
| SCD11 | M | 37 | Sleep | None | n/a × 168 | 360 | AC (RV) | FFPET |
| SCD12 | M | 25 | Rest | Dyspnoea | n/a | 360 | AC (RV) | FFPET |
| SCD13 | F | 14 | Sleep | None | n/a | 260 | AC (RV, LV) | n/a |
| SCD14 | F | 21 | Light activity | none | n/a × 160 | 310 | HCM | FFPET |
| SCD15 | F | 22 | Sleep | n/a | n/a | 220 | HCM | n/a |
| SCD16 | F | 35 | Rest | n/a | 87 × 171 | 365 | HCM | n/a |
| SCD17 | F | 45 | Rest | Dyspnoea | n/a | 290 | AC (RV) | FFPET |
| SCD18 | M | 20 | Rest | None | n/a × 178 | 360 | HCM | FFPET |
| SCD19 | M | 40 | n/a | n/a | n/a × 180 | 530 |
Non-diagnostic autopsy findings (foci of fatty replacement of the myocardium, RV) |
Autoptic blood |
| SCD20 | F | 50 | Rest | n/a | n/a × 164 | 300 | AC (RV) | Autoptic blood |
| SCD21 | F | 29 | Light activity | Syncope | n/a | n/a | MVP (Myxomatous degeneration of the mitral valve leaflets) | Autoptic blood |
| SCD22 | M | 42 | Sleep | None | n/a | n/a | SAD | Autoptic blood |
| SCD23 | M | 34 | Light activity | Syncope | n/a | n/a |
Non-diagnostic autopsy findings (small foci of fibrosis) |
Autoptic blood |
| SCD24 | M | 31 | Rest | Fever | n/a × 188 | 415 |
Non-diagnostic autopsy findings (foci of fatty replacement of the myocardium, LV) |
Autoptic blood |
| SCD25 | F | 37 | Light activity | n/a | n/a | 530 | SAD | Autoptic blood |
| SCD26 | M | 23 | Rest | n/a | n/a × 190 | 565 |
Non-diagnostic autopsy findings (mild fatty replacement, RV, LV) |
Autoptic blood |
| SCD27 | M | 50 | Light activity | None | n/a | 630 | HCM | Autoptic blood |
| SCD28 | M | 29 | Sport | Syncope | n/a | 380 | SAD | Autoptic blood |
| SCD29 | M | 42 | Light activity | None | n/a | 540 | Non-diagnostic autopsy findings (slightly dilated chambers and mild fatty replacement of the myocardium) | Autoptic blood |
| SCD30 | M | 40 | Rest | Chest pain | n/a | 450 |
Non-diagnostic autopsy findings (small foci of fibrosis) |
Autoptic blood |
| SCD31 | F | 45 | Rest | Chest pain | n/a | 286 | SAD | Autoptic blood |
| SCD32 | M | 29 | Sport | n/a | n/a × 184 | 315 | AC (RV, LV) | Autoptic blood |
| SCD33 | M | 50 | Sport | n/a | n/a | 510 |
Non-diagnostic autopsy findings (mild fatty replacement, RV, LV) |
Autoptic blood |
| SCD34 | M | 45 | n/a | n/a | n/a | n/a | SAD | Autoptic blood |
| SCD35 | M | 39 | Light activity | Palpitations | 175 × n/a | 575 | HCM | Autoptic blood |
| SCD36 | F | 50 | Sport | n/a | 173 × 70 | 300 | HCM | Autoptic blood |
| SCD37 | M | 42 | Sleep | None | 185 × 90 | 610 | HCM | Autoptic blood |
| SCD38 | F | 50 | Rest | None | 160 × 80 | 400 | SAD | Autoptic blood |
| SCD39 | F | 45 | Rest | None | 160 × 60 | 200 | SAD | Autoptic blood |
AC arrhythmogenic cardiomyopathy, HCM hypertrophic cardiomyopathy, DCM dilated cardiomyopathy, SAD sudden arrhythmic death, MVP mitral valve prolapse, LV left ventricle, RV right ventricle, FFPET formalin-fixed and paraffin-embedded tissue, n/a not available