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T-helper 17 induced signaling pathway A) Lung tissue real-time PCR mRNA expression. B) Serum ELISA for TH-17 pathway mediators. PCR values are presented as Log 2-fold change values. Data are presented as mean ± SD of n = 4–6 mice per group and analyzed by Two-way analysis of variance (ANOVA) followed by Tukey's post hoc test. * represents significantly different (P ≤ 0.05) from PBS + Air while # presents significantly (P ≤ 0.05) different between HDM + Air and HDM + O3.
