Fig. 4.

VinTS and VinTL lifetime in (a) 2D monolayers and (b) 3D multicellular aggregates after treatment with the Rho-associated kinase inhibitor Y-27632. VinTS-C and VinTL-C are controls treated with sterile water, VinTS-Y and VinTL-Y are treated with 10µM Y-27632. * p < 0.05 (ANOVA with repeated measured followed by Fisher's Least Significance Difference post-hoc test). Each point within the box plot represents a separate experiment. The boxes length extends from the minimum to the maximum value and the line denotes the mean. Results of multi-comparisons statistics tests may be found in Supplement 1 ^{(1.7MB, pdf)} .