Table 1.
Birth size and cord IGF-II levels by offspring H19 2992 genotype (ALSPAC cohort)
| CC | CT | TT | PA | PD | |
| (n = 1075) | (n = 518) | (n = 54) | |||
| Weight (gm) | 3468 ± 488 | 3522 ± 486 | 3524 ± 587 | 0.03 | 0.02 |
| Length (cm) | 50.7 ± 2.0 | 50.9 ± 2.0 | 50.9 ± 2.1 | 0.08 | 0.06 |
| Head circ. (cm) | 34.9 ± 1.2 | 34.9 ± 1.3 | 35.0 ± 1.6 | 0.3 | 0.4 |
| (n = 226) | (n = 110) | (n = 13) | |||
| Cord IGF-II (ng/dl) | 275 ± 78 | 277 ± 79 | 337 ± 91 | 0.1 | 0.3 |
Mean ± SD, adjusted for sex, gestation and parity.
PA = P value for additive genetic model (per T allele)
PD = P value for dominant genetic model (CC versus T/*)