Table 5.
Size at 3 years, and growth from birth, by offspring H19 2992 genotype, (ALSPAC cohort)
Offspring genotype | CC | CT | TT | PA | PD |
(n = 946) | (n = 462) | (n = 41) | |||
Weight at 3 y (kg) | 15.0 ± 1.7 | 14.9 ± 1.7 | 14.8 ± 1.7 | 0.4 | 0.4 |
Height at 3 y (cm) | 95.6 ± 3.6 | 95.3 ± 3.5 | 95.2 ± 3.7 | 0.2 | 0.2 |
Change in Weight SDS 0–3 y | 0.01 ± 1.17 | -0.13 ± 1.07 | -0.10 ± 1.29 | 0.01 | 0.02 |
Change in Height SDS 0–3 y | 0.06 ± 1.12 | -0.10 ± 1.02 | -0.17 ± 1.26 | 0.01 | 0.01 |
Mean ± SD, adjusted for sex and age
PA = P value for additive genetic model (per T allele)
PD = P value for dominant genetic model (CC versus T/*)