Table 2.

Inflammation in bronchial biopsies from smokers with COPD and asymptomatic smokers

	Total COPD	Symptomatic smokers	Asymptomatic smokers
	GOLD I-III	GOLD 0
Biopsies, n	19	8	24
CD3, %positive area	1.05 (0.2–9.24)	0.68 (0.19–1.7)	0.76 (0.17–2.4)
CD4, %positive area	0.041 (0.01–0.57)	0.073 (0–0.18)	0.04 (0–0.15)
CD8, %positive area	0.27 (0.03–2.55)	0.19 (0.02–1.53)	0.33 (0.3–1.25)
CD4/CD8 ratio	0.19 (0.1–4.4)	0.39 (0.04–1.2)	0.18 (0–0.91)
CD20, %positive area	0.003 (0–3.40)	0.003 (0–0.23)	0.005 (0–0.12)
NP57, %positive area	0.025 (0–0.13)	0.05 (0–0.23)	0.021 (0–0.36)
CD68, %positive area	0.035 (0–0.21)	0.056 (0–0.16)	0.041 (0–0.32)
EG2, %positive area	0.021 (0–0.31)	0.049 (0–0.15)	0.063 (0–0.59)
AA1, %positive area	0.15 (0.01–0.91)	0.22 (0–0.41)	0.22 (0.1–1.16)

Values expressed in median (range). Abbreviations: CD20 = B-cell marker, NP57 = neutrophil elastase, CD68 = macrophages, EG2 = eosinophils, AA1 = mast cell tryptase.