Fig. 7.

Royal jelly (RJ) is used as anti-aging by preventing the neurodegeneration through the reduction in oxidative stress, because RJ increases the GSH content and accelerating the activities of antioxidative enzymes such as SOD, CAT, G6PDH, GR, GPX and GST. Moreover, RJ decreases the secretion of inflammatory cytokines by down-regulating the inflammatory pathways and hence protects the neurons from damages and prevents the aging. Royal jelly suppresses the progression and development of tumors by inhibiting te angiogenesis, activation of immune system and prevents the metastasis and tumorgenesis.