Table 1.
Demographic and clinical characteristics of children in Latin America diagnosed with multisystem inflammatory syndrome in children.
| Characteristica | N (%) or median (interquartile range) |
|---|---|
| Age, years | 6.5 (2.8,10.6) |
| Sex | |
| Male | 699 (56.4%) |
| Ethnicity | |
| Mestizo | 800 (64.6%) |
| White | 304 (24.5%) |
| Unknown | 98 (7.9%) |
| Afro-Latino | 25 (2.0%) |
| Indigenous | 12 (1.0%) |
| Clinical characteristics | |
| Abdominal pain | 804 (64.9%) |
| Conjunctival injection | 784 (63.3%) |
| Rash | 759 (61.3%) |
| Emesis | 692 (55.9%) |
| Diarrhea | 573 (46.2%) |
| Extremity changes | 513 (41.5%) |
| Cervical lymphadenopathy | 360 (29.1%) |
| Strawberry tongue | 325 (26.2%) |
| Myalgia | 290 (23.4%) |
| Arthralgia | 200 (16.2%) |
| Arthritis | 87 (7.0%) |
| Days of fever on admission | 5 (4, 7) |
| Laboratory data | |
| White blood cells, cells/µL | 11,300 (7,400, 16,100) |
| Neutrophils, cells/µL | 7720 (4,209, 11,920) |
| Lymphocytes, cells/µL | 1260 (680, 2,380) |
| Bands, cells/µL | 40 (0, 376) |
| Platelet count, platelets/µL | 190,000 (112,000, 293,750) |
| Z-hemoglobin | −1.7 (−3.2, 0.3) |
| ESR, mm/hour | 39 (22, 60) |
| CRP, mg/dL | 14.0 (6.4, 24.4) |
| Sodium, mEq/L | 135 (132, 138) |
| ALT, IU/L | 40 (22, 79) |
| AST, IU/L | 43 (28, 80) |
| GGT, IU/L | 52 (22, 131.8) |
| Albumin, g/dL | 3.0 (2.6, 3.6) |
| Procalcitonin, ng/mL | 3.6 (0.8, 14.0) |
| Creatinine, mg/dL | 0.5 (0.3, 0.7) |
| Globulins, g/dL | 2.7 (2.2, 3.2) |
| Total bilirubin, mg/dL | 0.5 (0.3, 0.7) |
| Direct bilirubin, mg/dL | 0.2 (0.1, 0.5) |
| Indirect bilirubin, mg/dL | 0.3 (0.2, 0.5) |
| ALP, U/L | 168 (126, 245) |
| CPK, U/L | 61 (32, 142) |
| LDH, U/L | 317 (249, 468) |
| Triglycerides, mg/dL | 180 (123, 268) |
| Ferritin, ng/mL | 440 (226, 927) |
| ProBNP, pg/mL | 1275 (304, 6689.3) |
| Troponin, ng/mL | 0.05 (0.01, 0.27) |
| Cortisol, ug/dL | 22.1 (14.7, 60.1) |
| Prothrombin, sec | 14 (12.6, 15.9) |
| Thromboplastin, sec | 32.9 (28.2, 38.5) |
| INR | 1.2 (1.1, 1.3) |
| Fibrinogen, g/L | 5.2 (3.8, 7.2) |
| Dimer D, mg/L | 2.7 (1.5, 4.9) |
ALT, alanine aminotransferase; ALP, alkaline phosphatase; AST, aspartate aminotransferase; CPK, creatine kinase; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; GGT, gamma glutamyl-transferase; INR, international normalized value; LDH, dehydrogenase lactic; proBNP, pro B-type natriuretic peptide.
Total number of subjects for whom each characteristic was available was available: age: 1238; sex: 1239; ethnicity: 1239; abdominal pain: 1239; conjunctival injection: 1239; rash: 1239; vomit: 1239; diarrhea: 1239; extremity changes: 1236; cervical lymphadenopathy: 1239; strawberry tongue: 1239; myalgia: 1238; arthralgia: 1237; arthritis: 1238; days of fever on admission: 1226; white blood cells: 1231; neutrophils: 1068; lymphocytes: 1213; bands: 430; platelet count: 1230; Z-hemoglobin: 1234; ESR: 922; CRP: 1169; sodium: 1171; ALT: 1208; AST: 1209; GGT: 535; albumin: 1161; procalcitonin: 599; creatinine: 1189; globulins: 549; total bilirubin: 1012; direct bilirubin: 963; indirect bilirubin: 917; ALP: 697; CPK: 547; LDH: 1001; triglycerides: 553; ferritin: 1041; proBNP: 566; troponin: 806; cortisol: 18; prothrombin: 1132; thromboplastin: 1103; INR: 927; fibrinogen: 1043; D dimer: 1138.