Table 2.
Comparison of demographic and clinical characteristics among the training, internal validation, and external validation data(The following 20 variables have demonstrated significance through single-factor analysis).
| Variable | Training |
Internal validation |
Derivation |
|---|---|---|---|
| 674 | 290 | 964 | |
| Uroabc | |||
| Uro = 0,n(%) | 610(90.5 %) | 256(88.3 %) | 866(89.8 %) |
| Uro = 1,n(%) | 46(6.8 %) | 27(9.3 %) | 73(7.6 %) |
| Uro = 2,n(%) | 14(2.1 %) | 4(1.4 %) | 16(1.7 %) |
| Uro = 3,n(%) | 3(0.4 %) | 2(0.7 %) | 7(0.7 %) |
| Uro = 4,n(%) | 1(0.1 %) | 1(0.3 %) | 2(0.2 %) |
| HCIac | |||
| HCI = 0,n(%) | 487(72.3 %) | 195(67.2 %) | 682(70.7 %) |
| HCI = 1,n(%) | 187(27.7 %) | 95(32.8 %) | 282(29.3 %) |
| Risk Levelac | |||
| Risk Level = 0,n(%) | 629(93.3 %) | 265(91.4 %) | 894(92.7 %) |
| Risk Level = 1,n(%) | 45(6.7 %) | 25(8.6 %) | 70(7.3 %) |
| NIHSSabc | |||
| NIHSS = 1,n(%) | 106(15.7 %) | 47(16.2 %) | 153(15.9 %) |
| NIHSS = 2,n(%) | 323(47.9 %) | 134(46.2 %) | 457(47.4 %) |
| NIHSS = 3,n(%) | 195(28.9 %) | 87(30.0 %) | 282(29.3 %) |
| NIHSS = 4,n(%) | 30(4.5 %) | 12(4.1 %) | 42(4.4 %) |
| NIHSS = 5,n(%) | 20(3.0 %) | 10(3.4 %) | 30(3.1 %) |
| mRSabc | |||
| mRS = 0,n(%) | 447(66.3 %) | 185(63.8 %) | 632(65.6 %) |
| mRS = 1,n(%) | 227(33.7 %) | 105(36.2 %) | 332(34.4 %) |
| ChEc,u/L | 7301.5 [7011.35 | 7176.32 [7011.35, 7341.30] | 726.385 [7011.35, |
| , 7341.30] | 7341.30] | ||
| LymCabc,10^9/L | 1.75 [1.70, 1.86] | 1.78 [1.70, 1.86] | 1.76 [1.70, 1.86] |
| NLRabc | 3.72 [3.10, 3.60] | 3.35 [3.10, 3.60] | 3.61 [3.10, 3.60] |
| LymRabc | 0.24 [0.22, 0.24] | 0.23 [0.22, 0.24] | 0.24 [0.22, 0.24] |
| MonoCabc,10^9/L | 0.64 [0.64, 0.71] | 0.67 [0.64, 0.71] | 0.65 [0.64, 0.71] |
| PltCac,10^9/L | 245.98 [237.08, 258.68] | 247.88 [237.08, 258.68] | 246.55 [237.08, 258.68] |
| WBCac,10^12/L | 7.71 [7.69, 8.31] | 8 [7.69, 8.31] | 7.8 [7.69, 8.31] |
| Fibac,g/L | 3.76 [3.73, 4.02] | 3.87 [3.73, 4.02] | 3.8 [3.73, 4.02] |
| Gluabc, mmol/L | 6.25 [5.96, 6.63] | 6.29 [5.96, 6.63] | 6.26 [5.96, 6.63] |
| Kac,mmol/L | 3.65 [3.63, 3.72] | 3.68 [3.63, 3.72] | 3.66 [3.63, 3.72] |
| TGac, mmol/L | 1.52 [1.27, 1.41] | 1.34 [1.27, 1.41] | 1.47 [1.27, 1.41] |
| ApoAIac,g/L | 1.19 [1.14, 1.20] | 1.17 [1.14, 1.20] | 1.18 [1.14, 1.20] |
| LDHac,U/L | 189.77 [181.40, 195.08] | 188.24 [181.40, 195.08] | 189.31 [181.40, 195.08] |
| D_dimerac,ng/ml | 950.31 [742.98, 1213.36] | 978.17 [742.98, 1213.36] | 958.69 [742.98, 1213.36] |
| SBPabc, mmHg | 147.6 [144.05, 148.79] | 146.42 [144.05, 148.79] | 147.25 [144.05, 148.79] |
Continuous variables are presented as mean (confidence interval), while categorical variables are presented as numbers (percentages). The derivation dataset includes both training and internal validation data. In the column of significance, “a” indicates a significant difference between unfavorable discharge outcomes and favourable discharge outcomes in the derivation dataset, “b” indicates a significant difference between unfavorable discharge outcomes and favourable discharge outcomes in the training set, and “c” indicates a significant difference between unfavorable discharge outcomes and favourable discharge outcomes in the internal validation set.
ChE:Cholinesterase; LymC:Lymphocyte count; NeutR:Ratio of neutrophils; LymR:Ratio of lymphocytes; MonoC:Monocyte ratio; PltC:Platelet Count; WBC:White cell count; Fib:Plasma fibrinogen content; Glu:Glucose; TG:Triglycerides; ApoAI:ApolipoproteinAI; LDH:Lactate dehydrogenase; SBP:Systolic blood pressure on admission; HCI:History of cerebral infarction; Risk Level:Level of risk; NIHSS:National Institutes of Health Stroke Scale; mRS:Modified Rankin Scale; Uro:Urobilinogen.
The Uro was graded according to its reading: a reading of 0 was defined as grade 0, a reading of 0 or less than or equal to 34 as grade 1, a reading of 34 or less than or equal to 68 as grade 2, a reading of 68 or less than or equal to 135 as grade 3, a reading of 135 or less than or equal to 202 as grade 4, and a reading of more than 202 as grade 5.NIHSS score was divided into five grades: Grade 1 (0 points), Grade 2 (1–4 points), Grade 3 (5–15 points), Grade 4 (16–20 points), and Grade 5 (21–42 points). The discharge mRS (modified Rankin Scale) assessment results were divided into two grades: Grade 1 (0–1 points) and Grade 2 (3–6 points).