Table 2.
Estimated mean laboratory measurements by group after propensity score weighting
| Prior SARS-CoV-2 Infection |
No Prior Infection |
PASC score ≥12 | PASC score=0 | |
|---|---|---|---|---|
| Lab Measurement | Est (95% CI) | Est (95% CI) | Est (95% CI) | Est (95% CI) |
| Sodium (mmol/L) | 139.1 (139.1, 139.2) | 139.2 (139.0, 139.4) | 139.2 (139.1, 139.3) | 139.2 (139.0, 139.4) |
| Potassium (mmol/L) | 4.16 (4.15, 4.16) | 4.16 (4.12, 4.19) | 4.16 (4.14, 4.18) | 4.16 (4.13, 4.19) |
| Chloride (mmol/L) | 103.4 (103.3, 103.5) | 103.6 (103.3, 103.9) | 103.2 (103.0, 103.3) | 103.3 (103.1, 103.6) |
| Bicarbonate (mmol/L) | 25.2 (25.2, 25.3) | 25.1 (24.9, 25.4) | 25.2 (25.1, 25.3) | 25.0 (24.7, 25.2) |
| Creatinine (serum) (umol/L) | 77.5 (76.2, 78.7) | 75.4 (72.5, 78.3) | 78.4 (75.3, 81.5) | 76.7 (73.8, 79.6) |
| Creatinine (serum) (mg/dL) | 0.876 (0.862, 0.890) | 0.853 (0.820, 0.886) | 0.887 (0.852, 0.922) | 0.868 (0.835, 0.900) |
| Calcium (mmol/L) | 2.35 (2.35, 2.36) | 2.36 (2.35, 2.37) | 2.36 (2.35, 2.36) | 2.35 (2.34, 2.36) |
| Calcium (mg/dL) | 9.43 (9.42, 9.44) | 9.47 (9.44, 9.51) | 9.45 (9.43, 9.47) | 9.43 (9.39, 9.46) |
| ALT (U/L) | 22.6 (22.2, 22.9) | 22.1 (20.6, 23.6) | 23.3 (22.5, 24.2) | 22.8 (21.4, 24.1) |
| AST (U/L) | 21.8 (21.5, 22.1) | 21.9 (19.9, 23.8) | 22.0 (21.3, 22.6) | 22.2 (21.1, 23.3) |
| Total bilirubin (umol/L) | 9.56 (9.44, 9.67) | 9.45 (9.06, 9.84) | 9.09 (8.87, 9.32) | 9.13 (8.76, 9.51) |
| Total bilirubin (mg/dL) | 0.559 (0.552, 0.565) | 0.553 (0.530, 0.575) | 0.532 (0.519, 0.545) | 0.534 (0.512, 0.556) |
| Albumin (g/L) | 43.9 (43.8, 44.0) | 44.2 (43.8, 44.5) | 44.0 (43.9, 44.2) | 43.7 (43.4, 44.0) |
| WBC (x10^9 cells/L) | 6.58 (6.53, 6.63) | 6.63 (6.42, 6.84) | 6.90 (6.80, 7.00) | 6.88 (6.62, 7.15) |
| ALC (x10^9 cells/L) | 195.2 (193.3, 197.1) | 198.1 (189.3, 207.0) | 198.3 (194.9, 201.8) | 198.3 (189.7, 206.9) |
| ANC (x10^9 cells/L) | 392.5 (388.7, 396.2) | 394.5 (379.1, 410.0) | 421.0 (412.1, 429.9) | 410.1 (392.8, 427.3) |
| Hgb (g/L) | 136.1 (135.8, 136.4) | 137.2 (135.9, 138.5) | 136.4 (135.7, 137.1) | 136.3 (135.1, 137.6) |
| Platelets (x10^9 cells/L) | 265.9 (264.5, 267.4) (a) | 275.2 (268.5, 282.0) (a) | 272.7 (269.4, 276.0) | 266.3 (259.9, 272.7) |
| INR | 1.02 (1.02, 1.03) | 1.02 (1.01, 1.03) | 1.02 (1.01, 1.03) | 1.02 (0.99, 1.05) |
| D-dimer (ug/L) | 517.6 (497.8, 537.4) | 536.8 (481.6, 591.9) | 518.6 (476.2, 561.1) | 580.0 (471.8, 688.3) |
| hsCRP (mg/L) | 4.08 (3.93, 4.23) | 3.65 (3.18, 4.12) | 5.01 (4.62, 5.39) (a) | 4.23 (3.70, 4.76) (a) |
| Cystatin-C (mg/L) | 0.895 (0.886, 0.904) | 0.887 (0.863, 0.911) | 0.918 (0.899, 0.937) | 0.933 (0.884, 0.981) |
| HbA1c (%) | 5.58 (5.56, 5.60) (a) | 5.46 (5.40, 5.51) (a) | 5.63 (5.59, 5.67) | 5.67 (5.59, 5.74) |
| HDL cholesterol (mmol/L) | 1.50 (1.49, 1.51) | 1.49 (1.45, 1.52) | 1.47 (1.45, 1.49) | 1.47 (1.43, 1.50) |
| HDL cholesterol (mg/dL) | 57.9 (57.5, 58.2) | 57.4 (56.0, 58.8) | 56.9 (56.1, 57.6) | 56.7 (55.4, 57.9) |
| Non-HDL cholesterol (mmol/L) | 3.38 (3.36, 3.40) | 3.33 (3.24, 3.41) | 3.52 (3.47, 3.57) | 3.49 (3.40, 3.59) |
| Non-HDL cholesterol (mg/dL) | 130.7 (129.8, 131.5) | 128.6 (125.4, 131.8) | 136.2 (134.3, 138.0) | 135.0 (131.3, 138.8) |
| TSH (mcIU/mL) | 1.95 (1.91, 1.99) | 2.04 (1.85, 2.23) | 2.00 (1.90, 2.10) | 2.00 (1.86, 2.15) |
| NT-Pro BNP (pg/mL) | 83.7 (76.4, 91.1) | 80.8 (64.3, 97.2) | 83.1 (67.1, 99.0) | 124.6 (51.1, 198.1) |
| Albumin/creatinine ratio (mg/g) | 81.9 (67.5, 96.2) (a) | 43.0 (25.4, 60.6) (a) | 67.0 (43.5, 90.5) | 72.2 (42.7, 101.7) |
(a)
Non-overlapping 95% CI between groups.
ALT, alanine transaminase; AST, aspartate aminotransferase; WBC, white blood cell count; ALC, absolute lymphocyte count; ANC, absolute neutrophil count, Hgb, hemoglobin; INR, international normalized ratio; hsCRP, high-sensitivity C-reactive protein; HbA1c, hemoglobin A1c; HDL, high density lipoprotein; TSH, thyroid stimulating hormone; NT-Pro BNP, N-terminal pro b-type natriuretic peptide