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Half-Lives of IYD Proteolysis by Trypsin Incubated with O2N Ligandsa
| ligand | t1/2 (min)b | fold increase in t1/2 |
|---|---|---|
| O2N-tyrosinamide | 30 ± 2 | 3.0 |
| O2N-tyramine | 27 ± 9 | 2.7 |
| O2N-HPLA | 21 ± 4 | 2.1 |
Values and error were obtained from fitting two independent measurements at each time point to a first-order decay in Origin 6.0.
See Figures S16 and S17.
