Table 1.

Relaxivities of monomeric and tetrameric probes bearing CBP1 and CBP2 peptide moieties, in PBS and 0.6 mM human serum albumin (HAS) at 20 MHz and 37 °C

Compound$	r1 mM (mM−1 s−1)
	PBS	HSA 0.6 mM
Gadovist45	3.7	6.1*
Gd-DOTAMA-CBP1	7.4 ± 0.1	8.3 ± 0.2
Gd-DOTAMA-CBP2	8.8 ± 0.2	10.4 ± 0.2
[Gd-DOTAMA]4-CBP1
• per molecule	27.2 ± 0.4	28.6 ± 0.4
• per Gd(III)	6.8 ± 0.1	7.2 ± 0.1

^$ All Gd concentrations were confirmed by inductively coupled plasma (ICP) and/or bulk magnetic susceptibility (BMS)⁹⁰; * in non-sterile bovine plasma (corresponding to an albumin concentration of 0.64 to 0.82 mmol/L)^19,21,45,50.