TABLE 3.
Multipotency and heterogeneity of statins in osteoarthritis, knee osteoarthritis, and hip osteoarthritis.
| Exposure | Outcome | Pleiotropy test | Heterogeneity test | ||
|---|---|---|---|---|---|
| P (Mendelian randomization –Egger intercept) | P (Mendelian randomized PRESSO) | P (Mendelian randomized Egger Q) | P (inverse-variance weighting Q) | ||
| Statins | Osteoarthritis | 0.658 | 0.115 | 0.128 | 0.141 |
| Knee osteoarthritis | 0.6 | 0.015 | 0.013 | 0.015 | |
| Hip osteoarthritis | 0.141 | 0.404 | 0.614 | 0.579 | |