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. 2024 Sep 4;15:1390387. doi: 10.3389/fgene.2024.1390387

TABLE 3.

Multipotency and heterogeneity of statins in osteoarthritis, knee osteoarthritis, and hip osteoarthritis.

Exposure Outcome Pleiotropy test Heterogeneity test
P (Mendelian randomization –Egger intercept) P (Mendelian randomized PRESSO) P (Mendelian randomized Egger Q) P (inverse-variance weighting Q)
Statins Osteoarthritis 0.658 0.115 0.128 0.141
Knee osteoarthritis 0.6 0.015 0.013 0.015
Hip osteoarthritis 0.141 0.404 0.614 0.579