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. 2024 Sep 4;15:1426323. doi: 10.3389/fphar.2024.1426323

FIGURE 1.

FIGURE 1

(A) The conventional pharmacovigilance approach involves applying a single detection method to SRS data to generate a single ranking of ADRs pairs. This ranking is subsequently submitted to a committee of medical experts. (B) The approach proposed in this paper entails the application of Q distinct signal detection methods to EHC data, resulting in Q rankings. These rankings are then amalgamated into a unified ranking using the Borda count method. The consolidated ranking is then presented to the committee. Furthermore, the option to conduct a verification study is provided to the committee as well. The * indicates that, preferably, the EHC data are split into two sets: one for detection and one for the verification phase.