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. 2024 Aug 26;35(4):102315. doi: 10.1016/j.omtn.2024.102315

Figure 2.

Figure 2

m6A modifications and the mechanisms of their involvement in regulating disease-associated macrophages

(A) Mettl3, Mettl14, and Fto regulate the phenotype of brain macrophages through distinct response mechanisms. (B) Mettl3 regulates liver macrophages. (C) Igf2bp2, Ythdf2, and Mettl3 regulate the phenotype of lung macrophages. (D) Igf2bp2 regulates the phenotype of gastrointestinal macrophages. (E) Alkbh5 regulates the phenotype of cardiac macrophages.