Fig. 3.

Change from baseline in A OSDI scores, B Schirmer’s test scores, C TBUT, and D central corneal sensitivity at weeks 1 and 3 (FAS population). A OSDI scores (expressed as means and SDs) of the HPG/HA and CMC/HA groups were 8.1 (7.9) vs.  – 7.7 (7.4), p = 0.799 at week 1 and  – 9.9 (9.0) vs.  – 8.2 (12.0), p = 0.506 at week 3. B Schirmer’s test scores (expressed as means and SDs) of HPG/HA and CMC/HA groups were 1.6 (6.4) vs. 2.8 (5.1) mm/ 5 min, p = 0.373 at week 1 and 1.8 (6.3) vs. 2.4 (5.7) mm/ 5 min, p = 0.688 at week 3. C TBUT (expressed as means and SDs) of HPG/HA and CMC/HA groups were 0.6 (2.2) vs.  – 0.1 (1.8) s, p = 0.184 at week 1 and 0.5 (2.6) vs. 0.0 (2.1) s, p = 0.389 at week 3. D Central corneal sensitivity measurements (expressed as means and SDs) of HPG/HA and CMC/HA groups were 0.0 (0.2) vs.  – 0.0 (0.5), p = 0.854 at week 1 and 0.0 (0.3) vs. 0.1 (0.4), p = 0.275 at week 3. *p < 0.05. CMC carboxymethylcellulose, FAS full analysis set, HA hyaluronic acid, HPG hydroxypropyl guar, OSDI Ocular Surface Disease Index, TBUT tear break-up time