TABLE 7.

TK mutations identified in Pcv^r HSV-2 SB5 plaque isolates

Clonal virus	Mutationa		Predicted length (aa)b
	Nucleotide	Amino acid
2P1	+T7	FS 3	31
2P2	C863T; +C1003	G39E; T288M; FS 335	390
2P4	ΔC467	FS 156	182
2P5	C863T; ΔT927	T288M; FS 309
2P6	G676A; ΔAC862–863	E226K; FS 290	347
2P7	+A366; ΔG439; ΔC471; ΔC476; ΔT482; +T917	FS 122, 147, 157, 159, 161, 306	347
2P8	G116A; C863T	G39E; T288M	376
2P9	C573A; C863T; +A923	F191L; T288M; FS 308	390
2P10	ΔT419	FS 140	182

^aThe designation C863T represents a change from the wild-type nucleotide C to a T at base 863; the others follow this pattern. Δ, base deletion; +, base insertion; FS, frameshift in the coding sequence. 

^baa, amino acid.