Table 1.

A compilation of nsSNPs predicted to be highly deleterious by nine computational methods.

Rs no	A.A. change	SIFT	MAPP	PANTHER	SNP&GO	PHD-SNP	Predict-SNP	SNAP2	PolyPhen1	PolyPhen2
Rs73317647	R165C	DL	DL	DL	D	D	DL	E	DL	PD
Rs139489847	G296R	DL	DL	DL	D	D	DL	E	DL	PD
Rs140404252	L74R	DL	DL	DL	D	D	DL	E	DL	PD
Rs141730422	H54R	DL	DL	DL	D	D	DL	E	DL	PD
Rs142407509	W152R	DL	DL	DL	D	D	DL	E	DL	PD
Rs145677283	R165H R165L	DL	DL	DL	D	D	DL	E	DL	PD
Rs149524118	A216T	DL	DL	DL	D	D	DL	E	DL	PD
Rs201697165	S182F	DL	DL	DL	D	D	DL	E	DL	PD
Rs746249658	R138L R138Q	DL	DL	DL	D	D	DL	E	DL	PD
Rs751350884	S182P	DL	DL	DL	D	D	DL	E	DL	PD
Rs762384069	H301N	DL	DL	DL	D	D	DL	E	DL	PD
Rs763719329	H304P H304L	DL	DL	DL	D	D	DL	E	DL	PD
Rs765852756	I141N	DL	DL	DL	D	D	DL	E	DL	PD
Rs771191320	W136G	DL	DL	DL	D	D	DL	E	DL	PD
Rs771330275	V219E	DL	DL	DL	D	D	DL	E	DL	PD
Rs776903420	S230R	DL	DL	DL	D	D	DL	E	DL	PD
Rs780551100	I349N	DL	DL	DL	D	D	DL	E	DL	PD
Rs866700996	L303R	DL	DL	DL	D	D	DL	E	DL	PD
Rs1035358113	R215G	DL	DL	DL	D	D	DL	E	DL	PD
Rs1255515664	W306C	DL	DL	DL	D	D	DL	E	DL	PD
Rs1264823419	H137P	DL	DL	DL	D	D	DL	E	DL	PD
Rs1271726667	L111R	DL	DL	DL	D	D	DL	E	DL	PD
Rs1300885615	E140A	DL	DL	DL	D	D	DL	E	DL	PD
Rs1305371427	S234R	DL	DL	DL	D	D	DL	E	DL	PD
Rs1325443204	L308Q	DL	DL	DL	D	D	DL	E	DL	PD
Rs1586608274	Q227R	DL	DL	DL	D	D	DL	E	DL	PD
Rs1822266670	D103V	DL	DL	DL	D	D	DL	E	DL	PD
Rs1822805541	L222R	DL	DL	DL	D	D	DL	E	DL	PD
Rs2130999340	L146R	DL	DL	DL	D	D	DL	E	DL	PD

DL: deleterious; D: disease; E: effect; PD: probably damaging.