Table 7.
Fold changes in serum of specific functional differentially abundant proteins in piglets weaned on low iron diets (n = 6).
| Accession no. | Gene name | Protein name | Annotation | Fold change (L-Fe/control) | P-value |
|---|---|---|---|---|---|
| Platelet function | |||||
| B3STX9 | – | Prothrombin | Prothrombin | 1.22 | 0.093 |
| B6ECP2 | GPIbA | Glycoprotein Ib platelet subunit alpha | Platelet glycoprotein Ib alpha polypeptide | 0.67 | 0.037 |
| Immune response | |||||
| A0SEG9 | C9 | Complement component C9 | Complement component C9 | 0.80 | 0.009 |
| B6ECP2 | GPIbA | Glycoprotein Ib platelet subunit alpha | Platelet glycoprotein Ib alpha polypeptide | 0.67 | 0.037 |
| F1RS37 | POSTN | Periostin | Uncharacterized protein | 0.76 | 0.041 |
| R4H4K5 | – | Retinoic acid receptor responder protein 2 | Chemerin | 1.24 | 0.013 |
| F1SUE4 | ASPN | Asporin | Uncharacterized protein | 1.27 | 0.003 |
| I3L5Z3 | PRG4 | – | Uncharacterized protein | 0.74 | 0.003 |
| I3LKU0 | RAC3 | Rac family small GTPase 3 | Uncharacterized protein | 1.56 | 0.029 |
| F1S8U2 | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase | Uncharacterized protein | 0.38 | 0.031 |
| K7ZRK0 | IGHA | IgA heavy chian constant region | IgA heavy chain constant region (fragment) | 1.24 | 0.032 |
| L8AXM9 | IGHG | IgG heavy chain | IgG heavy chain | 0.66 | 0.005 |
| I3LQP7 | TMBIM6 | Bax inhibitor 1 | Bax inhibitor 1 | 0.61 | <0.001 |
| C0JPM4 | TIMP-2 | Metalloproteinase inhibitor-2 | Tissue inhibitor of metalloproteases 2 | 0.64 | 0.019 |
| Cell metabolism | |||||
| I3LQP7 | TMBIM6 | Bax inhibitor 1 | Bax inhibitor 1 | 0.61 | <0.001 |
| C0JPM4 | TIMP-2 | Metalloproteinase inhibitor-2 | Tissue inhibitor of metalloproteases-2 | 0.64 | 0.019 |
| O97765 | CTGF | Connective tissue growth factor | Connective tissue growth factor | 1.22 | 0.033 |
| I3LFF0 | PLCH1 | Phosphoinositide phospholipase C1 | Phosphoinositide phospholipase C1 | 1.40 | 0.005 |
| F1RSC3 | SCPEP1 | Carboxypeptidase 1 | Carboxypeptidase 1 | 1.60 | 0.041 |
| Transcription and protein syntheses | |||||
| B6DT15 | USP7 | Ubiquitin carboxyl-terminal hydrolase 7 | Ubiquitin-specific peptidase 7 | 0.65 | 0.050 |
| F2Z557 | PABPC3 | Polyadenylate-binding protein 3 | Polyadenylate-binding protein 3 | 0.78 | 0.044 |
| F2Z5K2 | PSMA5 | Proteasome subunit alpha type5 | Proteasome subunit alpha type5 | 0.81 | 0.034 |
| F1SBA5 | PSMA8 | Proteasome subunit alpha type 8 | Proteasome subunit alpha type8 | 0.69 | 0.007 |
| A5D9J4 | PSMB8 | Proteasome subunit beta 8 | Proteasome subunit beta type8 | 0.83 | 0.011 |
| A1XQU1 | PSMB7 | Proteasome subunit beta type 7 | Proteasome subunit beta type7 | 0.75 | 0.005 |
| Q29387 | EEF1G | Elongation factor 1-gamma | Elongation factor 1-gamma | 1.21 | 0.028 |
| Q0PY11 | EEF1A | Elongation factor 1-alpha | Elongation factor 1-alpha | 1.35 | 0.023 |