Table 1.
Baseline characteristics.
Characteristics | Infarct subtype | Total (n = 1568) | ||
---|---|---|---|---|
Small subcortical infarct (n = 517) | Large subcortical and cortical infarct (n = 759) | Infratentorial infarct (n = 361) | ||
Female, n (%) | 235 (45.5) * | 290 (38.2) * | 121 (33.5) * | 626 (39.9) * |
Age in years, mean (SD) | 66.3 (11.7) * | 67.7 (11.7) * | 68.1 (11.4) * | 67.3 (11.5) * |
Education, n (%) | ||||
Lower than secondary school | 265 (51.3) * | 398 (52.4) * | 188 (52.1) * | 816 (52.0) * |
Secondary school | 122 (23.6) * | 164 (21.6) * | 71 (19.7) * | 343 (21.9) * |
Technical school or college | 57 (11.0) * | 65 (8.6) * | 33 (9.1) * | 153 (9.8) * |
University or higher | 73 (14.1) * | 132 (17.4) * | 69 (19.1) * | 256 (16.3) * |
Baseline NIHSS, mean (SD) | 2.5 (2.5) # | 4.3 (4.9) # | 3.1 (3.6) # | 3.5 (4.0) # |
History of stroke and TIA, n (%) | 64 (12.9) # | 114 (15.0) # | 51 (14.1) # | 217 (14.4) # |
Imaging characteristics | ||||
Normalized acute infarct volume (mL), median (IQR) | 1.1 (1.2) * | 11.2 (22.2) * | 1.7 (6.7) * | 2.6 (11.4) * |
Presence of an old infarct, n (%) | 73 (14.1) | 177 (23.3) | 73 (20.2) | 302 (19.3) |
Normalized WMH volume (mL), median (IQR) | 8.3 (17.0) * | 6.0 (15.4) * | 8.6 (18.7) * | 7.1 (16.4) * |
Cognitive performance, mean (SD) | ||||
MoCA | 23.5 (4.0) * | 22.3 (4.6) $ | 23.5 (9.4) $ | 23.0 (4.4) $ |
Domain z-score | ||||
Attention and executive functioning (n = 1470) | −0.6 (1.0) # | −0.9 (1.1) # | −0.6 (1.0) # | −0.7 (1.0) # |
Information processing speed (n = 1467) | −0.5 (1.1) # | −0.8 (1.2) # | −0.5 (1.0) # | −0.6 (1.2) # |
Language (n = 1537) | −0.6 (1.0) # | −0.9 (1.1) # | −0.7 (1.0) # | −0.7 (1.1) # |
Verbal memory (n = 1545) | −0.8 (1.2) # | −1.1 (1.3) # | −0.9 (1.1) # | −0.9 (1.2) # |
SD: standard deviation; NIHSS: National Institutes of Health Stroke Scale; TIA: transient ischemic attack; IQR: interquartile range; WMH: white matter hyperintensity; MoCA: Montreal Cognitive Assessment.
Patients with multiple infarcts can be represented in more than one stroke category.
Missing in < 1%.
Missing in 1–10%.
Missing in > 10%.