Figure 4.

Networks of differentially co-expressed genes

(A) Network of DCLs of hub genes involved in 48 gene-gene interactions among themselves in PD-ND group, filtered by DCGs.

(B) Network of DCLs of hub genes involved in 23 gene-gene interactions exclusive co-expressed genes in PD-D group, filtered by DCGs.

(C) Top 10 most significant biological processes enriched for differentially co-expressed genes in the PD-ND.

(D) Top 10 most significant biological processes enriched for differentially co-expressed genes in the PD-D.

(E) Overall intersection of co-expression and differential co-expression results in PD-ND group.

(F) Overall intersection of focused LID co-expression and differential co-expression results. PD-D, people with Parkinson’s disease with levodopa-induced dyskinesia; PD-ND, people with Parkinson’s disease without levodopa-induced dyskinesia; DCGs, differentially co-expressed genes; DCLs, differentially co-expressed links.