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. 2024 Aug 26;27(9):110820. doi: 10.1016/j.isci.2024.110820

Figure 3.

Figure 3

Serum lipids measured in morbid obese and lean control individuals (cohort 2)

(A) Volcano plot of the differentially abundant lipids in serum between obese and lean control subjects. Colored dots highlight significant up- or down-regulated individual lipid species (fold change ≥1.5 and p < 0.05, Welch’s corrected).

(B) Lipid class repartition (PC, PE, PI, CL, HexCer, Cer, and SM) in human serum from lean control and obese individuals (in mol %).

(C) Relative PC level changes (mol %) in serum collected from lean control and obese individuals, clustered according to the chain length, LC (long chain C28-34), VLC (very long chain C38-44).

(D) Relative PC level changes (mol %) in serum collected from lean control and obese individuals, represented according to the degree of saturation.

(E) Relative SM level changes (mol %) in serum collected from lean control and obese individuals, clustered according to the chain length. Statistics for (B–E) are unpaired Student’s t test p values. Data from obese (n = 16) and control (n = 5) individuals are represented as mean ± SEM. ∗p < 0.05, ∗∗p < 0.01; ∗∗∗p < 0.001.