REAGENT or RESOURCE	SOURCE	IDENTIFIER
Biological samples
Serum and adipose tissue samples from morbid obese subjects before and after GBS intervention	University Hospital of Geneva (Montecucco et al., 2015)14	Geneva ethical commission approval number 2017-00133.
Serum and VAT samples from morbid obese non T2D individuals (cohort 2)	Université Clermont Auvergne, France (Hannich et al., 2020)9	French Ethical Committee SUD EST IV (Agreement 12/111
Chemicals, peptides, and recombinant proteins
PC 12:0/12:0	Avanti Polar Lipids Inc.	Cat#850335; CAS: 18194-25-7
PE 17:0/14:1	Avanti Polar Lipids Inc.	Cat#LM-1104; CAS: 958763-89-8
PI 17:0/14:1	Avanti Polar Lipids Inc.	Cat#LM-1504; CAS: 1246304-61-9
PS 17:0/14:1	Avanti Polar Lipids Inc.	Cat#LM-1304; CAS: 1036814-91-1
Cer d18:1/17:0	Avanti Polar Lipids Inc.	Cat#860517; CAS: 67492-16-4
SM d18:1/12:0	Avanti Polar Lipids Inc.	Cat#860583; CAS: 474923-21-2
HexCer d18:1/8:0	Avanti Polar Lipids Inc.	Cat#860540; CAS: 111956-47-9
MTBE (methyl-tert-butyl ether)	Sigma Aldrich	Cat#34875; CAS : 1634-04-4
Methylamine solution(33% in absolute ethanol)	Sigma Aldrich	Cat#534102; CAS: 74-89-5
Chloroform	Acros Organics	Cat#326820010; CAS: 67-66-3
Methanol	Acros Organics	Cat#CAS: 67-56-1
n-butanol	Acros Organics	Cat#CAS: 71363
Ammonium molybdate(VI) tetrahydrate	Acros Organics	Cat#CAS: 12054-85-2
Monopotassium phosphate	Sigma Aldrich	Cat#60229; CAS: 7778-77-0
L-ascorbic acid	Sigma Aldrich	Cat#A92902; CAS: 50-81-7
Perchloric acid 70%	Sigma Aldrich	Cat#244252 ; CAS : 7601-90-3
Hexane	ThermoFisher Scientific	CAS: 110-54-3
Methyl acetate	Sigma Aldrich	CAS: 79-20-9
Acetonitrile	Sigma Aldrich	CAS: 75-05-8
Software and algorithms
TSQ Tune 2.6 SP1 QuickQuan™ Software	ThermoFisher Scientific	Catalog number: IQLAAEGABSFAHQMAPT; https://www.thermofisher.com/order/catalog/product/IQLAAEGABSFAHQMAPT
Xcalibur 4.0 QF2 software	ThermoFisher Scientific	Catalog number: OPTON-30965; https://www.thermofisher.com/order/catalog/product/OPTON-30965
LcmsExplorer	EPFL Lausanne Switzerland	http://lipidomes.epfl.ch/
Lipid Data Analyzer	IGB-TUG Graz University	LDA v. 2.6.3.9; https://www.lipidmaps.org/resources/tools/10?task=4.5
MetaboAnalyst 5.0.	McGill University, Canada	https://www.metaboanalyst.ca/MetaboAnalyst/ModuleView.xhtml
Prism Graph Pad 8.0.	Graphpad	https://www.graphpad.com/
Other
Precellys 24 tissue homogenizer	Bertin Instruments	https://www.bertin-instruments.com/product/sample-preparation-homogenizers/precellys24-tissue-homogenizer/precellys24-4/
Zirconium oxide beads CK14	Labgene Scientific SA	Cat#BER20305