No.	Recommendations/Statements	GoR	LoE	Sources
5.1	Simple endometrial hyperplasia without atypia should not be treated by hysterectomy.	B	3	1 ,  2
5.2	Hysterectomy may be considered for complex endometrial hyperplasia without atypia.	0	3	1
5.3	In postmenopausal patients and in premenopausal patients with completed family planning and presence of atypical hyperplasia of the endometrium, total hysterectomy with bilateral salpingectomy and, if necessary, bilateral ovariectomy shall be performed.	A	1	2 ,  3
5.4	In the presence of atypical hyperplasia, the ovaries may be left in place when performing hysterectomy and bilateral salpingectomy in premenopausal women, provided there is no evidence of a hereditary predisposition to ovarian cancer (e.g., BRCA mutation or certain forms of Lynch syndrome).	EC
5.5	If uterus preservation is desired, the uterus and adnexa may be left in place in the presence of atypical hyperplasia if the patient has been informed that the standard treatment almost always leading to cure is total hysterectomy, agrees to close monitoring and has been informed of the need for hysterectomy after the desire for a child has been fulfilled or abandoned.	EC
5.6	If uterus preservation is desired, the uterus and adnexa may be left in place in the presence of atypical hyperplasia if a hysteroscopy with targeted biopsy or with curettage was performed to confirm the diagnosis and the diagnosis “atypical hyperplasia” was made or confirmed by a pathologist experienced in gynecologic pathology.	EC
5.7	If uterus preservation is desired, the uterus and adnexa may be left in place in the presence of atypical hyperplasia if laparoscopy with vaginal ultrasound or MRI has been performed to best assess the risk of adnexal involvement and/or myometrial infiltration.	EC
5.8	If complete remission of AEH is seen after 6 months of conservative treatment, planned pregnancy should be pursued.	EC
5.9	If there is currently no desire to have a child, maintenance therapy shall be performed. An endometrial biopsy should be performed every 6 months.	EC
5.10	After fulfillment or abandonment of the desire to have children, a total hysterectomy (+/− bilateral salpingectomy +/−, bilateral ovariectomy) shall be performed.	A	4	4 ,  5 ,  6 ,  7 ,  8