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. 2023 Aug 15;83(8):963–995. doi: 10.1055/a-2066-2068
No. Recommendations/Statements GoR LoE Sources
9.4 If local recurrence in the vagina or pelvis is suspected or if distant metastases are suspected, histological confirmation shall be sought. EC
9.5 Cross-sectional imaging shall be performed if vaginal recurrence, pelvic recurrence or distant metastasis is suspected or after histologic confirmation of vaginal recurrence, pelvic recurrence or distant metastasis. A 3 58 ,  68 ,  69
9.6 Women with isolated vaginal or vaginal stump recurrence after endometrial cancer without prior radiation therapy as part of primary treatment should receive radiation therapy with curative intent, consisting of external pelvic radiation and brachytherapy with or without local tumor resection. EC
9.7 Women with isolated vaginal or vaginal stump recurrence after endometrial cancer with adjuvant brachytherapy alone as part of primary treatment, radiotherapy with or without local tumor resection may be given with curative intent. EC
9.8 Women with vaginal or vaginal stump recurrence in status post external pelvic irradiation with or without brachytherapy, should be evaluated to determine whether new radiotherapy as external irradiation or brachytherapy with or without local tumor resection in curative intention is possible. EC
9.9 Local late effects of radiotherapy shall be treated according to the S3 Guideline “Supportive therapy in oncology patients” 87 . EC