No. | Recommendations/Statements | GoR | LoE | Sources |
---|---|---|---|---|
9.13 | There is no evidence that endocrine therapy improves duration of survival or survival rate or progression-free survival in women with recurrence after endometrial cancer compared with other therapies or best supportive care. | EC | ||
9.14 | Endocrine therapy with MPA (200–250 mg/d) or MGA (160 mg/d) or tamoxifen (20 mg/d or 40 mg/d) or a combination of tamoxifen and MPA/MGA can be given to women with recurrence after endometrial cancer. | 0 | 3 | 70 , 71 , 72 , 73 , 74 |
9.15 | In women with recurrence after endometrial cancer, endocrine therapy with MPA or tamoxifen results in higher response rates when progesterone receptor expression or estrogen receptor expression or well to-moderate tumor differentiation (G1/G2) is detectable. | ST | 3 | 70 , 72 , 73 , 75 |