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. 2023 Aug 15;83(8):963–995. doi: 10.1055/a-2066-2068
No. Recommendations/Statements GoR LoE Sources
7.16 Patients with endometrioid endometrial carcinoma (type I) and positive lymph nodes, involvement of the uterine serosa, adnexa, vagina, bladder, or rectum (stages III-IVA) should receive adjuvant percutaneous radiotherapy followed by simultaneous chemotherapy or, alternatively, chemotherapy alone in combination with vaginal brachytherapy. B 3,5 40 ,  46
7.17 Patients with endometrioid EC (type I) and positive lymph nodes, involvement of the uterine serosa, adnexa, vagina, bladder, or rectum (stages III–IVA) can alternatively receive adjuvant chemotherapy followed by percutaneous radiotherapy. EC
7.18 If simultaneous radiochemotherapy followed by chemotherapy is chosen, the regimen used in the PORTEC-3 trial should be applied. EC
7.19 When chemotherapy is combined with vaginal brachytherapy alone, brachytherapy can be given after or between chemotherapy administrations. EC