Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Formation of liver immunosuppressive tumor microenvironment. The formation of immunosuppressive microenvironment of liver cancer promotes the immune escape. The reduced antigen presentation by immunoregulatory cells leads to the impaired T cell effects. The heterogeneity of TME and chronic liver diseases lead to the suppression of immune function and immune response. Liver is exposed to intestinal antigens and obtains immune tolerance.
