FIG. 3.

Infectivity of viral particles produced by cells with a wild-type or altered Gag/Gag-Pol ratio. Freshly isolated PBMCs were phytohemagglutinin stimulated for 3 days and then infected with either wild-type or mutant virus. Supernatants were collected 3, 7, 10, and 14 days (d) after infection, and the RT activity in each sample was measured. The results shown represent the mean and standard deviation of triplicate samples. Open symbols represent viruses derived from cells with an excess of PR(+) Gag-Pol, and closed symbols (except asterisks) represent viruses derived from cells with excess of PR(−) Gag-Pol. Symbols: ∗, wild-type virus; ⧫ and ◊, progeny viruses of cells with a predicted 20:3.5 Gag/Gag-Pol ratio; ▴ and ▵, predicted 20:6 Gag/Gag-Pol ratio; ■ and □, predicted 20:11 Gag/Gag-Pol ratio; ● and ○, predicted 20:21 Gag/Gag-Pol ratio.