Table 2.
Threshold effect analyses of total moderate-to-vigorous physical activity (MVPA) on the risk of incident nonalcoholic fatty liver disease (NAFLD) using two-piecewise regression models
| Total MVPA, min/week | Total | Events(ratea) | Crude model | Adjusted modelb | ||
|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |||
| < 208 | 40,059 | 386 (1.4) | 0.51 (0.43, 0.61) | < 0.001 | 0.68 (0.57, 0.81) | < 0.001 |
| ≥ 208 | 48,597 | 176 (0.5) | 0.89 (0.82, 0.96) | 0.004 | 0.91 (0.84, 0.99) | 0.028 |
aIncidence rates were expressed as per 10,000 person-years
bAdjusted for age, sex, ethnicities, recruitment center, Townsend deprivation index, educational attainment, household income, employment, smoking status, alcohol consumption, body mass index, and the total time and season of accelerometer wear