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. 2024 Sep 18;22:398. doi: 10.1186/s12916-024-03618-2

Table 2.

Threshold effect analyses of total moderate-to-vigorous physical activity (MVPA) on the risk of incident nonalcoholic fatty liver disease (NAFLD) using two-piecewise regression models

Total MVPA, min/week Total Events(ratea) Crude model Adjusted modelb
HR (95% CI) P value HR (95% CI) P value
 < 208 40,059 386 (1.4) 0.51 (0.43, 0.61)  < 0.001 0.68 (0.57, 0.81)  < 0.001
 ≥ 208 48,597 176 (0.5) 0.89 (0.82, 0.96) 0.004 0.91 (0.84, 0.99) 0.028

aIncidence rates were expressed as per 10,000 person-years

bAdjusted for age, sex, ethnicities, recruitment center, Townsend deprivation index, educational attainment, household income, employment, smoking status, alcohol consumption, body mass index, and the total time and season of accelerometer wear