Table 3.

Association of moderate-to-vigorous physical activity (MVPA) patterns with study outcomes

MVPA patterns	Events(ratea)	Crude model		Adjusted modelb
		HR/OR(95% CI)	P value	HR/OR(95% CI)	P value
Primary outcome: incident nonalcoholic fatty liver disease
Inactive	322 (16.7)	Ref		Ref
Active weekend warrior	154 (6.3)	0.37 (0.31, 0.45)	< 0.001	0.55 (0.44, 0.67)	< 0.001
Active regular	86 (5.7)	0.34 (0.27, 0.43)	< 0.001	0.49 (0.38, 0.63)	< 0.001
Secondary outcomes
Incident severe liver diseases
Inactive	220 (11.4)	Ref		Ref
Active weekend warrior	178 (7.3)	0.64 (0.52, 0.77)	< 0.001	0.75 (0.61, 0.93)	0.008
Active regular	106 (7.0)	0.61 (0.49, 0.77)	< 0.001	0.76 (0.59, 0.97)	0.025
Incident liver cirrhosis
Inactive	186 (9.6)	Ref		Ref
Active weekend warrior	159 (6.5)	0.67 (0.54, 0.83)	< 0.001	0.80 (0.64, 0.99)	0.045
Active regular	91 (6.0)	0.62 (0.48, 0.80)	< 0.001	0.76 (0.58, 0.99)	0.041
Liversteatosis
Inactive	1352 (29.5)	Ref		Ref
Active weekend warrior	1410 (20.1)	0.60 (0.55,0.65)	< 0.001	0.74 (0.67,0.81)	< 0.001
Active regular	654 (17.0)	0.49 (0.44,0.54)	< 0.001	0.60 (0.53,0.67)	< 0.001
Liver fibrosis
Inactive	264 (7.4)	Ref		Ref
Active weekend warrior	206 (3.6)	0.47 (0.39,0.57)	< 0.001	0.62 (0.51,0.76)	< 0.001
Active regular	89 (2.8)	0.36 (0.28,0.46)	< 0.001	0.48 (0.37,0.62)	< 0.001

^aIncidence rates were expressed as per 10,000 person-years for incident nonalcoholic fatty liver disease, incident severe liver diseases, and incident liver cirrhosis, while rates were expressed as percentage for liver fat and liver fibrosis

^bAdjusted for age, sex, ethnicities, recruitment center, Townsend deprivation index, educational attainment, household income, employment, smoking status, alcohol consumption, body mass index, and the total time and season of accelerometer wear