Fig. 5. CCR2 is necessary for optimal HSPC homing to the BM.

(A) Experimental schematic of competitive homing using WT and Ccr2^gfp/gfp BM (n = 8). (B) Flow cytometric analysis measuring the relative frequency of CCR2⁺ versus GFP⁺ (CCR2⁻) cells, including lineage-positive and lineage-negative cells within the CD45.2 cell compartment 20 hours after transplantation. (C) Representative flow cytometry plots and quantitative analysis of CD45.2⁺ CCR2⁺ versus CD45.2⁺ GFP⁺ cells across each subpopulation. Experimental schematics created using BioRender. **P < 0.01 and ***P < 0.001.