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. Author manuscript; available in PMC: 2024 Sep 18.
Published in final edited form as: Essays Biochem. 2021 Dec 17;65(6):877–886. doi: 10.1042/EBC20200164

Figure 1.

Figure 1.

A. Structures of CsnB and related compounds and celastrol B. Mechanisms associated with PDNPA inducing dissociation of NR4A1 from p38 (51) and (B) effects of celastrol and oxidized DIM compounds inducing nuclear export of NR4A1 which forms a pro-apoptotic NR4A1-bcl2 complex that target mitochondria (54).