Table 3. a) Proportion of infant participants age 0–5 months and 6–11 months by reported history of infection and maternal history of infection and/or vaccination b) Seroprevalence of SARS-CoV-2 spike and nucleocapsid antibody estimated from blood samples taken from infants aged 0–5 months and 6–11 months by maternal infection and/or vaccination status prior to delivery.
| a) | |||||||
|---|---|---|---|---|---|---|---|
| Maternal infection pre-delivery n/N (%) |
Maternal vaccination pre-delivery n/N (%) |
Both infected and vaccinated n/N (%) |
|||||
| Age: 0–5 months a | |||||||
| Reported infection in the infant | |||||||
| Yes | 0/14 (0.0) | 7/48 (14.6) | 0/12 (0.0) | ||||
| No | 14/14 (100.0) | 41/48 (85.4) | 12/12 (100.0) | ||||
| Age: 6–11 months b | |||||||
| Reported infection in the infant | |||||||
| Yes | 0/2 (0.0) | 15/32 (46.9) | 0/1 (0.0) | ||||
| No | 2/2 (100.0) | 17/32 (53.1) | 1/1 (100.0) | ||||
| b) | |||||||
| No reported prior infection in the infant | Reported prior infection in the infant | ||||||
| Spike antibody n/N (%) | Nucleocapsid antibody n/N (%) | Spike antibody n/N (%) | Nucleocapsid antibody n/N | ||||
| Maternal infection pre-delivery (yes/no) | |||||||
| Infants aged 0–5 months | |||||||
| Yes | 12/14 (85.7) | 4/14 (28.6) | 0/0 (0.0) | 0/0 (0.0) | |||
| No | 25/26 (96.2) | 3/26 (11.5) | 8/9 (88.9) | 7/9 (77.8) | |||
| Infants aged 6–11 months | |||||||
| Yes | 2/2 (100.0) | 0/2 (0.0) | 0/0 (0.0) | 0/0 (0.0) | |||
| No | 2/33 (66.7) | 5/33 (15.2) | 22/23 (95.7) | 21/23 (91.3) | |||
| Maternal vaccination pre-delivery (yes/no) | |||||||
| Infants aged 0–5 months | |||||||
| Yes | 41/41 (100.0) | 7/41 (17.1) | 7/7 (100.0) | 6/7 (85.7) | |||
| No | 3/7 (42.9) | 2/7 (28.6) | 2/3 (66.7) | 2/3 (66.7) | |||
| Infants aged 6–11 months | |||||||
| Yes | 15/17 (88.2) | 4/17 (23.5) | 15/15 (100.0) | 15/15 (100.0) | |||
| No | 17/28 (60.7) | 5/28 (7.9) | 16/17 (94.1) | 15/17 (88.2) | |||
| Maternal infection and vaccination pre-delivery (yes/no) | |||||||
| Infants aged 0–5 months | |||||||
| Yes | 12/12 (100.0) | 4/12 (33.3) | 0/0 (0.0) | 0/0 (0.0) | |||
| No | 25/28 (89.3) | 3/28 (10.7) | 8/9 (88.9) | 7/9 (77.8) | |||
| Infants aged 6–11 months | |||||||
| Yes | 1/1 (100.0) | 0/1 (0.0) | 0/0 (0.0) | 0/0 (0.0) | |||
| No | 23/34 (67.7) | 5/34 (14.7) | 22/23 (95.7) | 21/23 (91.3) | |||
a Of infants aged 0–5 months: Maternal infection status pre-delivery was recorded for 49 infants; 14/49 (71.4%) infants had reported maternal infection pre-delivery. Maternal vaccination status pre-delivery was recorded for 58 infants; 48/58 (82.8%) infants had reported maternal vaccination pre-delivery; Maternal infection and vaccination status pre-delivery was recorded for 49 infants; 12/49 (24.5%) infants had reported maternal infection and vaccination pre-delivery.
b Of infants aged 6–11 months: Maternal infection status pre-delivery was recorded for 58 infants; 2/58 (3.5%) infants had reported maternal infection pre-delivery. Maternal vaccination status pre-delivery was recorded for 77 infants; 32/77 (41.6%) infants had reported maternal vaccination pre-delivery; Maternal infection and vaccination status pre-delivery was recorded for N = 58 infants; 1/58 (1.7%) infants had reported maternal infection and vaccination pre-delivery.