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. 2024 Sep 5;18:1463038. doi: 10.3389/fnins.2024.1463038

Table 1.

Parameters of ultrasound-activated mechanosensitive ion channels.

Channel Frequency
(MHz)
Sound pressure
(MPa)
Duty cycle
(DC)
Pulse repetition frequency (PRF) Citation
MscL
MscL-G22S 10 0.095 25% 5 Hz Heureaux et al. (2014)
MscL-I92L 29.92 0.45 / / Ye et al. (2018)
MscL-G22S 0.5 0.05–0.35 40% 1 kHz Qiu et al. (2021)
TRP
TRP-4 2.25 0.9 Continuous waves Continuous waves Ibsen et al. (2015)
TRPA1 7 2.5 Continuous waves Continuous waves Duque et al. (2022)
TRPA1 0.43 0.673 50% 2 kHz Oh et al. (2019)
TRPP1 0.3 / Continuous waves Continuous waves Yoo et al. (2022)
TRPP2 0.3 / Continuous waves Continuous waves Yoo et al. (2022)
TRPM2 3.2 1.6 20% 10 Hz Yang et al. (2023)
K2P
TREK-1 10 / Continuous waves Continuous waves Kubanek et al. (2016)
TREK-2 10 / Continuous waves Continuous waves Kubanek et al. (2016)
TRAAK 10 / Continuous waves Continuous waves Kubanek et al. (2016)
TRAAK 4.78 / Continuous waves Continuous waves Sorum et al. (2021)
Piezo
Piezo1 0.5 0.3 40% 1 kHz Qiu et al. (2019)
Pizeo1 2 0.17 50% 1 kHz Shen et al. (2021)
Pizeo1 2 0.6 10% 5 Hz Zhang et al. (2020)
Pizeo1 0.3, 0.35, 0.4, 0.45 0.3–0.45 50% 1 kHz Zhu et al. (2023)