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. 2024 Sep 18;14:21802. doi: 10.1038/s41598-024-72142-3

Table 1.

Comparison of baseline data between the poor prognosis group and the good prognosis group.

Indicator Group χ2/t/Z P value
Good (mRS 0–2) (n = 46) Poor (mRS 3–6) (n = 31)
Clinical data
Sex
Male 33(71.74) 16(51.61) 3.242 0.072
Female 13(28.26) 15(48.39)
Age, years 59.13 ± 16.23 71.45 ± 13.77 − 3.467 0.001
BMI, kg/m2 24.43 ± 4.14 23.38 ± 3.85 1.087 0.281
APACHE II 9.61 ± 4.96 15 ± 5.2 − 4.584  < 0.001
CCI 0.43 ± 0.75 1.48 ± 1.36 − 3.905  < 0.001
NRS2002 2.87 ± 2.01 5.13 ± 2 − 4.856  < 0.001
Diagnosis (classification)
Cerebrovascular diseases 31(67.39) 21(67.74) /  > 0.999
CNS infectious diseases 5(10.87) 3(9.68)
Neuromyelitis optica 1(2.17) 1(3.23)
Epilepsy 7(15.22) 4(12.90)
Metabolic encephalopathy 1(2.17) 1(3.23)
Degenerative diseases of the nervous system 1(2.17) 1(3.23)
Previous history of neurological diseases
No 41(89.13) 28(90.32) /  > 0.999
Yes 5(10.87) 3(9.68)
Inflammatory indicators within the first day of admission
WBC, *109/L 9.63 ± 3.12 10.77 ± 4.72 − 1.181 0.244
ANC, *109/L 7.78 ± 3.12 8.56 ± 3.87 − 0.98 0.33
ALC, *109/L 1.22 ± 0.55 0.99 ± 0.51 1.806 0.075
AMC, *109/L 0.55 ± 0.23 0.61 ± 0.44 − 0.766 0.448
PLT, *109/L 208.96 ± 71.23 184.45 ± 60.1 1.574 0.12
NLR 8.62 ± 7.44 10.57 ± 6.77 − 1.171 0.245
PLR 196.58 ± 103.67 217.98 ± 106.03 − 0.876 0.384
hsCPR, mg/L 5.22(2.46,10.87) 14.91(6.21,20) − 3.317 0.001
Nutritional biochemical indicators
Alb(on admission), g/L 39.67 ± 5.02 37.32 ± 5.88 1.865 0.066
Hb(on admission), g/L 140.57 ± 16.48 127.29 ± 24.69 2.625 0.012
Hb(on admission)-Hb(min), g/L 9.5(5,20) 35(6,59) 3.166 0.002
Glu(on admission), mmol/L 6.5(5.4,8.9) 7.9(6.5,8.7) 1.369 0.171
BIA indicators within the first day of admission
BCM, kg 30.54 ± 5.1 27.1 ± 5.8 2.659 0.01
PA, degree 5.57 ± 0.86 4.06 ± 0.93 7.077  < 0.001
BCM/PA, kg/degree 5.53 ± 0.83 6.89 ± 1.64 − 4.04  < 0.001
ICW, L 21.33 ± 3.56 18.92 ± 4.06 2.663 0.01
ECW, L 13.27 ± 2.07 12.53 ± 2.41 1.396 0.167
TBW, % 0.38 ± 0.01 0.4 ± 0.01 − 6.733  < 0.001
FFM, kg 46.97 ± 7.57 42.57 ± 8.65 2.287 0.025
TBW/FFM, % 73.64 ± 0.38 73.79 ± 0.37 − 1.722 0.089
SMI, kg/m2 9.55 ± 1.32 8.53 ± 1.62 2.929 0.005
WBP, kg 9.21 ± 1.54 8.18 ± 1.75 2.649 0.01
VFA, cm2 93.9 ± 49.57 118.33 ± 63.64 − 1.834 0.071
Outcome indicators
Mortality rate within 3 months
Survival 46(100.00) 15(48.39) 29.969  < 0.001
Death 0(0.00) 16(51.61)
Mechanical ventilation time, days 0(0,0) 6(0,13) 4.597  < 0.001
NICU hospital stay, days 4(2,10) 13(7,23) 4.551  < 0.001
Total hospital stay, days 15.5(13,25) 25(13,37) 1.763 0.078
Hospitalization expenses, thousand yuan 29.15(20.11,69.84) 112.97(56.2,192.59) 4.072  < 0.001

Cerebrovascular diseases which include ischemic stroke, intracerebral hemorrhage; CNS infectious diseases = Central nervous system infection diseases, CNS infectious diseases which include N-methyl-D-aspartate receptors, tuberculous meningitis, viral encephalitis, toxoplasma encephalitis, purulent meningitis; Degenerative diseases of the nervous system which include parkinson's disease, Alzheimer's disease.