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. 2024 Sep 18;7:1172. doi: 10.1038/s42003-024-06850-x

Fig. 1. Flowchart of animal experiment and Effects of peptides from E. japonicus and G. max on clinical symptoms and intestinal mucosal barrier in mice of CDI.

Fig. 1

Different letters indicate significant difference between each group. (n = 5). A Flowchart of animal experiment. B Effects of peptides on the body weight in mice of CDI. C Counting the number of goblet cells in the colon of different groups of mice. D Effects of peptides on colonic Goblet cell in mice of CDI. (×200). E Effects of peptides on pathological changes of small intestine, cecum, and colon tissues in mice of CDI. (×200). Black arrow: inflammatory cell infiltration；Red arrow: goblet cells；Yellow arrow: mucosal epithelial cell erosion and detachment；Green arrow: submucosal edema. F Effects of peptides on colonic inflammatory factors. Pro-inflammatory factors: IL-6(Interleukin 6), TNF-α(Tumor Necrosis Factor-alpha), INF-γ:(Interferon -γ); Anti-inflammatory factors: IL-4(Interleukin 4), IL-10(Interleukin 10). Different lowercase letters represent significant differences between each other for the same indicator (P < 0.05), same as below.