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. 2024 Sep 18;15:8202. doi: 10.1038/s41467-024-52557-2

Fig. 6. Non-overlapping MIC (µg/ml) between ciprofloxacin (•) and BWC0977 (Δ) across clinical isolates.

Fig. 6

Scatter plot of individual MICs of 35–40 fluoroquinolone-resistant clinical isolates of E. coli, A. baumannii and P. aeruginosa, and 98 fluoroquinolone-resistant clinical isolates of K. pneumoniae. The MIC values of BWC0977 and ciprofloxacin are non-overlapping, indicating the lack of cross-resistance between ciprofloxacin and BWC0977, a finding that will support the use of BWC0977 for treating infections caused by fluoroquinolone-resistant bacterial pathogens.