Table 5.
Studies showing the role of various TLR7 SNP in viral infection and pathogenesis in different ethnic groups worldwide
Study | TLR7 Restriction site | Pathogen | Disease | Population |
---|---|---|---|---|
Fakhir 2017 [18] | rs179008 | HCV | Mediated hepatic illness | Moroccan patients |
Lauhkonen et al. 2016 [19] | rs179008 | Respiratory Syncytial Virus (RSV) | Post-bronchiolitis lung function deficiency | Finnish children 5 to 7 yrs of age |
Mukherjee et al. 2019 [16] | rs3853839 & rs179008 | Dengue virus infection | Significant ssociation with dengue | Indian |
Zhang et al. 2020 [14] | rs179010 | HIV | HIV-1 infection | Chinese Han |
Dutta et al. 2017 [17] | rs3853839 | Chikungunya virus | Chikungunya infection | Indians |
Yue et al. 2014 [15] | rs3853839 | HCV persistence and predisposition | Enterovirus-71-mediated hand, foot and mouth infection | Chinese |