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. 2024 Sep 18;160(11):1161–1170. doi: 10.1001/jamadermatol.2024.3121

Figure 3. Percentage of Patients With Worst Itch Numeric Rating Scale (WI-NRS) Success and Daily Changes.

Figure 3.

WI-NRS was evaluated on an 11-point scale ranging from 0 (no itch) to 10 (worst itch imaginable). WI-NRS success was defined as at least a 4-point reduction in WI-NRS from baseline in patients 12 years or older. CFB indicates change from baseline; LS, least squares.

aEvaluated in patients 12 years or older with baseline WI-NRS score of at least 4.

bEvaluated in all patients, not just those with baseline WI-NRS scores of at least 4.

cNominal P = .004 (INTEGUMENT-1) and P < .001 (INTEGUMENT-2) at 24 hours following the first application, and P < .05 at all subsequent time points, for difference vs vehicle.