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. 2024 Aug 31;96(37):14909–14917. doi: 10.1021/acs.analchem.4c02906

Table 1. Optical Conditions and Calculated S/N Ratios of Raman Spectra Obtained from Two E. coli K12 Colonies.

  spatial resolution [μm]
S/N ratio [-]
NA XY Z 750 cm–1 1130 cm–1 1580 cm–1 1660 cm–1
0.90 1.2 6.4 5.28 8.15 6.12 4.65
0.75 2.3 7.8 3.49 4.16 1.90 2.27
0.65 2.8 8.6 2.44 3.25 1.90 1.92
0.25 11 ∼240 2.13a 1.88a 1.52a 1.56a
a

For N = 1 owing to the weak signal.