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. 2024 Sep 19;22:576. doi: 10.1186/s12951-024-02789-7

Fig. 4.

Fig. 4

FA hydrogels accelerates the recovery of radiation-induced injury. (A) Progression of radiation-induced animal model establishment and FA gel administration. (B) Gross images of rat skin on the buttocks and back. (C) Evaluation of skin injury using the Douglas and Fowler score. (D) Recording of rat weight. (E) Histological analysis of skin tissues using HE staining (Black arrows indicate keratinization layer, and white arrows indicate inflammatory cells). (F) Detection of thickness of epidermal layer. (G-H) The fluorescence intensity of MPO, CD68, and CD3 in dermis and epidermis were evaluated. * p < 0.05, ** p < 0.01, *** p < 0.01 compared with the 40 Gy + Aloe gel, 40 Gy + 5% gel, 40 Gy + 10% gel, 40 Gy + 15% gel groups